FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.
The FDA has recently approved Clarinex-D 24 Hour (desloratadine 5 mg and pseudoephedrine sulfate USP 240 mg) extended release tablets to treat nasal and non-nasal symptoms of seasonal allergic rhinitis in patients 12 years of age or older. There were two 2-week trials, both demonstrating significantly greater efficacy of Clarinex-D 24 Hour for allergic rhinitis, compared to desloratidine or pseudoephedrine, which led to FDA approval of this combination 24-hour medication. Clarinex-D 24 Hour also provided significantly greater relief from nasal congestion compared to desloratadine.
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