Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Phenergan (promethazine) is now contraindicated in children younger than 2 years because of possible fatal respiratory depression and should be used cautiously in other pediatric patients, according to a new black box warning recently requested by the Food and Drug Administration. The agency requested that the black box warning be added to Phenergan's label after a review of the drug's pediatric adverse events.
Excessive sedation may occur when promethazine is combined with other medications that depress the central nervous system (brain) and cause sedation. Such drugs include ethanol, barbiturates, anti-anxiety medications, sedatives, other phenothiazines, and narcotic pain medications.
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