HOW TO USE: May be taken with food or milk to lessen stomach irritation. Do not take more medication than is prescribed. For motion sickness, medication should be taken 30-60 minutes before travel.
Call your doctor immediately if you experience twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. These could be early signs of dangerous side effects.
DRUG CLASS AND MECHANISM: Promethazine is a phenothiazine in the same drug class as chlorpromazine (Thorazine) and trifluoperazine (Stelazine). However, unlike the other drugs in this class, promethazine is not used as an anti-psychotic. It used as an anti-histamine, sedative, and antiemetic (anti-nausea). The body releases histamine during several types of allergic reactions. When histamine binds to its receptors on cells, it stimulates changes within the cells that lead to sneezing, itching, and increased mucus production.
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