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USES: Promethazine is used to prevent nausea and vomiting. It is also used for sedation, allergy symptoms (runny nose, itchy eyes) and motion sickness (prevention and treatment). Use is not recommended in children less than 2 years old.

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Phenergan (promethazine) is now contraindicated in children younger than 2 years because of possible fatal respiratory depression and should be used cautiously in other pediatric patients, according to a new black box warning recently requested by the Food and Drug Administration. The agency requested that the black box warning be added to Phenergan's label after a review of the drug's pediatric adverse events.

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Promethazine oral is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in your body. Promethazine oral is used to treat allergy symptoms such as itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes.

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